Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576164 | 0.88 | GRM2 (0.43) | HIF1AFOLH1MRGPRX4IDO1 | |
| SCHEMBL6577612 | 0.84 | CYP4F2 (0.53) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 | |
| SCHEMBL1926802 | 0.76 | CYP4F2 (0.76) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 | |
| SCHEMBL70173 | 0.74 | CYP4F2 (0.83) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 | |
| SCHEMBL6577714 | 0.72 | GRM2 (0.41) | HIF1AFOLH1MRGPRX4IDO1 | |
| SCHEMBL6574143 | 0.72 | CHRM2 (0.46) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 | |
| SCHEMBL1925403 | 0.72 | CYP4F2 (0.69) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 | |
| SCHEMBL6011697 | 0.72 | CYP4F2 (0.73) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 | |
| SCHEMBL6160155 | 0.70 | CYP4F2 (0.71) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 | |
| SCHEMBL14231980 | 0.70 | CYP4F2 (0.58) | CYP4F2CYP4A11SLC7A5LOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383730-A2 | ANTICHOLINERGIC COMPOUNDS AND METHODS OF USE | Aryx Therapeutics (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002096855-A2 | ANTICHOLINERGIC COMPOUNDS AND METHODS OF USE | ARYX THERAPEUTICS (US) | 2002-12-05 | — | — | WO | disclosed |