Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098342 | 0.86 | SLC6A2 (0.40) | ESR1ACP3ALDH1A1HPGDROCK2 | |
| SCHEMBL30423754 | 0.82 | TSHR (0.44) | ESR1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL9864216 | 0.79 | CTSA (0.45) | ACP3CTSA | |
| SCHEMBL4441244 | 0.76 | TRPA1 (0.47) | ESR1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL1857873 | 0.74 | ACP3 (0.43) | ESR1ACP3ALDH1A1HPGDMEN1 | |
| SCHEMBL5265776 | 0.73 | ESR1 (0.43) | ESR1ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL10699377 | 0.73 | TRPA1 (0.44) | ESR1ACP3GAACYP19A1 | |
| SCHEMBL28894794 | 0.73 | ESR1 (0.39) | ESR1ACP3ALDH1A1ROCK2MEN1 | |
| SCHEMBL22917035 | 0.72 | ESR1 (0.46) | ESR1ACP3ALDH1A1HPGDMEN1 | |
| SCHEMBL14371997 | 0.72 | ESR1 (0.46) | ESR1ACP3ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408883-A1 | BIOACTIVE SPINAL IMPLANT MATERIAL AND METHOD OF MANUFACTURE THEREOF | Vita Licensing Inc. (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003005937-A1 | BIOACTIVE SPINAL IMPLANT MATERIAL AND METHOD OF MANUFACTURE THEREOF | VITA LICENSING, INC. (US) | 2003-01-23 | — | — | WO | disclosed |