Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.51 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577323 | 0.88 | NLRP3 (0.67) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL6580505 | 0.86 | KMT2A (0.69) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL29200420 | 0.83 | MEN1 (0.66) | KMT2AMEN1ALDH1A1KCNQ2MAPT | |
| SCHEMBL30802696 | 0.83 | MEN1 (0.66) | KMT2AMEN1ALDH1A1KCNQ2MAPT | |
| SCHEMBL28019942 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1KCNQ2MAPT | |
| SCHEMBL7237004 | 0.83 | KDM4E (0.62) | KMT2AMEN1ALDH1A1KCNQ2MAPT | |
| SCHEMBL29200413 | 0.81 | MEN1 (0.66) | KMT2AMEN1ALDH1A1KCNQ2MAPT | |
| SCHEMBL30802681 | 0.81 | MEN1 (0.66) | KMT2AMEN1ALDH1A1KCNQ2MAPT | |
| SCHEMBL6579406 | 0.79 | KCNJ5 (0.69) | KMT2AALDH1A1MAPTKCNJ5KCNJ3 | |
| SCHEMBL11531211 | 0.79 | KMT2A (0.76) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |