Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 7/20 | 0.69 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.69 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | PRKX | P51817 | 1/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019937 | 0.83 | KCNJ5 (0.67) | KCNJ5KCNJ3KCNJ6LMNAMAPT | |
| SCHEMBL7243088 | 0.83 | KCNJ5 (0.67) | KCNJ5KCNJ3KCNJ6LMNAMAPT | |
| SCHEMBL30802690 | 0.81 | KCNJ5 (0.72) | KCNJ5KCNJ3KCNJ6LMNAMAPT | |
| SCHEMBL29200421 | 0.81 | KCNJ5 (0.72) | KCNJ5KCNJ3KCNJ6LMNAMAPT | |
| SCHEMBL6580505 | 0.81 | KMT2A (0.69) | LMNAMAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6577323 | 0.80 | NLRP3 (0.67) | KCNJ5KCNJ3KCNJ6LMNAMAPT | |
| SCHEMBL31729852 | 0.80 | KCNJ5 (0.74) | KCNJ5KCNJ3KCNJ6LMNAMAPT | |
| SCHEMBL6577877 | 0.79 | KMT2A (0.60) | KCNJ5KCNJ3MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30802695 | 0.78 | KCNJ5 (0.72) | KCNJ5KCNJ3KCNJ6LMNAMAPT | |
| SCHEMBL29200411 | 0.78 | KCNJ5 (0.72) | KCNJ5KCNJ3KCNJ6LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |