Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80897 | 0.83 | TSHR (0.41) | LTA4HTDP1L3MBTL1CA1CA2 | |
| SCHEMBL379025 | 0.74 | CA4 (0.37) | LTA4HCA1CA2MAOBTSHR | |
| SCHEMBL2252915 | 0.73 | TSHR (0.41) | LTA4HTDP1L3MBTL1CA1CA2 | |
| SCHEMBL12380718 | 0.72 | FFAR1 (0.35) | LTA4HL3MBTL1CA1CA2NPC1 | |
| SCHEMBL5831072 | 0.72 | CA1 (0.33) | CA1CA2HTTALDH1A1POLB | |
| SCHEMBL2227585 | 0.72 | TSHR (0.40) | LTA4HTDP1L3MBTL1CA1CA2 | |
| SCHEMBL5831071 | 0.71 | TSHR (0.32) | HTTALDH1A1TSHR | |
| SCHEMBL4881254 | 0.71 | MAOB (0.34) | MAOBALDH1A1TSHR | |
| SCHEMBL24027472 | 0.71 | TSHR (0.36) | CA1CA2HTTALDH1A1SIGMAR1 | |
| SCHEMBL13667172 | 0.70 | KMT2A (0.49) | TDP1L3MBTL1RAB9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019418-B1 | INOSITOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | BIONERIS AB (SE) | 2004-04-28 | — | — | EP | disclosed |