Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | KDM6B | O15054 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428878 | 0.84 | CTSK (0.53) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL4691184 | 0.84 | CTSK (0.53) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL6578194 | 0.83 | CTSK (0.56) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL5105817 | 0.82 | CTSK (0.49) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL5098711 | 0.81 | CTSK (0.64) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL7429714 | 0.81 | CTSK (0.64) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL6404534 | 0.81 | CTSK (0.64) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL6578193 | 0.81 | CTSK (0.48) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL5098703 | 0.79 | CTSK (0.52) | CTSKKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL6584080 | 0.79 | CTSK (0.52) | CTSKPOLBALDH1A1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |