Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | KAT7 | O95251 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578194 | 0.91 | CTSK (0.56) | CTSKCTSLCTSBCTSSCACNA1B | |
| SCHEMBL6578009 | 0.91 | CTSK (0.52) | CTSKCTSLCTSBCTSSCACNA1B | |
| SCHEMBL6580363 | 0.87 | CTSK (0.55) | CTSKCTSLCTSBCTSSF2 | |
| SCHEMBL6578319 | 0.87 | CTSK (0.51) | CTSKCTSLCTSBCTSSF2 | |
| SCHEMBL6580967 | 0.86 | CTSK (0.52) | CTSKKAT6ACTSLCTSBCTSS | |
| SCHEMBL7429714 | 0.82 | CTSK (0.64) | CTSKCTSLCTSBCTSSCACNA1B | |
| SCHEMBL5098711 | 0.79 | CTSK (0.64) | CTSKCTSLCTSBCTSSCACNA1B | |
| SCHEMBL6404534 | 0.79 | CTSK (0.64) | CTSKCTSLCTSBCTSSCACNA1B | |
| SCHEMBL6578142 | 0.79 | CTSK (0.48) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL4689761 | 0.79 | CTSK (0.63) | CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |