Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CASP6 | P55212 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | NT5E | P21589 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960299 | 0.93 | RAPGEF4 (0.51) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL10576785 | 0.91 | RAPGEF4 (0.55) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL4844624 | 0.87 | RAPGEF4 (0.46) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL8164203 | 0.87 | RAPGEF4 (0.58) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL10536585 | 0.87 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL8164756 | 0.84 | CA2 (0.43) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL17774590 | 0.84 | ALDH1A1 (0.44) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL9152694 | 0.84 | RAPGEF4 (0.55) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL8412044 | 0.84 | RAPGEF4 (0.55) | RAPGEF4ALDH1A1TDP1RECQLKDM4E | |
| SCHEMBL9153315 | 0.83 | RAPGEF4 (0.54) | RAPGEF4ALDH1A1TDP1RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102911523-A | Blue reactive dye and preparation method thereof | TIANJIN DEKAI CHEM IND CO LTD | 2013-02-06 | — | — | CN | claimed |
| CN-102911523-A | Blue reactive dye and preparation method thereof | TIANJIN DEKAI CHEM IND CO LTD | 2013-02-06 | — | — | CN | disclosed |
| EP-1036825-B1 | Reactive dyestuffs, process for their preparation and use thereof | CIBA SC HOLDING AG (CH) | 2004-05-06 | — | — | EP | disclosed |
| US-6592634-B1 | Dioxazine and triazine dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-15 | — | — | US | disclosed |
| EP-1036825-A1 | Reactive dyestuffs, process for their preparation and use thereof | Ciba SC Holding AG (CH) | 2000-09-20 | — | — | EP | disclosed |
| CN-1266870-A | Active dye, preparing method and use thereof | CIBA SC HOLDING AG (CH) | 2000-09-20 | — | — | CN | disclosed |
| EP-0356014-B1 | Reactive Dyes | ZENECA LTD (GB) | 1994-11-30 | — | — | EP | disclosed |
| EP-0311893-B1 | PROCESS FOR THE PREPARATION OF 2,5-BIS-(AMINOARYLAMINO)BENZOQUINONES | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0356014-A1 | Reactive Dyes | ZENECA LIMITED (GB) | 1990-02-28 | — | — | EP | disclosed |
| US-4851527-A | Water-soluble triphendioxazine compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| US-4400504-A | DYEING AND PRINTING CELLULOSE AND POLYAMIDE AND-URETHANE FIBERS; TRIAZINE, PYRIDINE AND PYRIMIDINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |