Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.65 |
| ▸ | CTSL | P07711 | 5/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580161 | 0.91 | CTSK (0.66) | CTSKCTSLCASP1CASP3CTSS | |
| SCHEMBL6580581 | 0.87 | CTSK (0.62) | CTSKCTSLCTSSCTSBTAOK1 | |
| SCHEMBL6581108 | 0.85 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6577984 | 0.85 | CTSK (0.64) | CTSKCTSLCASP1CASP3CTSS | |
| SCHEMBL6583815 | 0.83 | CASP1 (0.62) | CTSKCTSLCASP1CASP3 | |
| SCHEMBL6577927 | 0.81 | CASP1 (0.59) | CTSKCASP1CASP3 | |
| SCHEMBL6577777 | 0.80 | CTSK (0.65) | CTSKCTSLCASP1CASP3CTSS | |
| SCHEMBL6579813 | 0.80 | CTSK (0.67) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580544 | 0.79 | CTSK (0.59) | CTSKCTSLCASP1CASP3CTSS | |
| SCHEMBL5099344 | 0.79 | CTSK (0.57) | CTSKCTSLCTSSCTSBTAOK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |