Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5957753 | 0.90 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6537275 | 0.85 | MTNR1A (0.59) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6816867 | 0.84 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5957987 | 0.84 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL1548630 | 0.84 | LMNA (0.54) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL1549160 | 0.84 | LMNA (0.54) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL1548628 | 0.84 | LMNA (0.54) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5958304 | 0.83 | HPGD (0.57) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL1549021 | 0.83 | LMNA (0.53) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL1548635 | 0.83 | LMNA (0.53) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448514-A1 | NOVEL ALPHA-OXYGENATED OR ALPHA-THIOLATED CARBOXYLIC ACID PHENETHYLAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003042168-A1 | NOVEL α-OXYGENATED OR α-THIOLATED CARBOXYLIC ACID PHENETHYLAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | disclosed |