SCHEMBL6578291

SCHEMBL6578291

S=C(Nc1ccccc1)Nc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.80
MAPT P10636 8/20 0.80
KMT2A Q03164 7/20 0.80
HTT P42858 5/20 0.80
MEN1 O00255 4/20 0.80
CYP1A2 P05177 2/20 0.70
CYP2C19 P33261 2/20 0.70
ALOX12 P18054 7/20 0.70
HPGD P15428 2/20 0.70
CYP3A4 P08684 1/20 0.68
TAS2R38 P59533 1/20 0.68
HSD17B10 Q99714 1/20 0.68
GAA P10253 4/20 0.68
EPHX1 P07099 2/20 0.68
POLB P06746 1/20 0.68
LMNA P02545 6/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
NPSR1 Q6W5P4 2/20 0.63
PLA2G1B P04054 1/20 0.63
ATG4B Q9Y4P1 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7028772 0.98 KMT2A (0.77) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL14181848 0.89 KMT2A (0.71) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL11828149 0.87 MAPT (0.73) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL8956322 0.85 ALDH1A1 (0.94) ALDH1A1MAPTKMT2AMEN1CYP1A2
SCHEMBL5407086 0.83 MAPT (0.62) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL132620 0.82 ALDH1A1 (1.00) ALDH1A1MAPTKMT2AMEN1CYP1A2
SCHEMBL1259295 0.82 CYP1A2 (1.00) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL653550 0.82 ALDH1A1 (0.85) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL201794 0.82 ALDH1A1 (0.67) ALDH1A1MAPTKMT2AHTTMEN1
Hydrogen Sulfide SCHEMBL28246712 0.81 CYP1A2 (0.96) ALDH1A1MAPTKMT2AHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1120435-B1 APPARATUS AND METHOD FOR PRODUCING RESIN TEIJIN LTD (JP) 2004-05-06 EP disclosed
US-6562936-B1 Resin excellent in hydrolysis and heat stability such as a reduction in molecular weight at the time of molding and color retention and moldability such as releasability and transferability, rarely experiences residence deterioration TEIJIN LIMITED (JP) 2003-05-13 US disclosed
US-6509435-B1 Heat resistance, stability; moldings TEIJIN LIMITED (JP) 2003-01-21 US disclosed
CN-1371399-A Polycarbonate, process for producing the same and molded article thereof TEIJIN LTD (JP) 2002-09-25 CN disclosed
EP-1191049-A1 POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-03-27 EP disclosed
EP-1120435-A1 APPARATUS AND METHOD FOR PRODUCING RESIN TEIJIN LIMITED (JP) 2001-08-01 EP disclosed