Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.77 |
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 4/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578291 | 0.98 | ALDH1A1 (0.80) | KMT2AMAPTALDH1A1MEN1HTT | |
| SCHEMBL14181848 | 0.91 | KMT2A (0.71) | KMT2AMAPTALDH1A1MEN1HTT | |
| SCHEMBL8956322 | 0.87 | ALDH1A1 (0.94) | KMT2AMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL11828149 | 0.85 | MAPT (0.73) | KMT2AMAPTALDH1A1MEN1HTT | |
| SCHEMBL132620 | 0.84 | ALDH1A1 (1.00) | KMT2AMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL1259295 | 0.84 | CYP1A2 (1.00) | KMT2AMAPTALDH1A1MEN1HTT | |
| Hydrogen Sulfide SCHEMBL28246712 | 0.82 | CYP1A2 (0.96) | KMT2AMAPTALDH1A1MEN1HTT | |
| SCHEMBL9470190 | 0.82 | ALDH1A1 (0.94) | KMT2AMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL8614488 | 0.82 | ALDH1A1 (0.64) | KMT2AMAPTALDH1A1MEN1HTT | |
| SCHEMBL5407086 | 0.81 | MAPT (0.62) | KMT2AMAPTALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973735-B1 | POLYAROMATIC ANTIVIRAL COMPOSITIONS | UPJOHN CO (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1148048-A2 | Polyaromatic antiviral compositions | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-24 | — | — | EP | disclosed |
| US-5958983-A | NOVEL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST HERPES, TOPICAL ADMINISTRATION THEM TO TREAT PATIENTS WITH HERPES; WORK BY INHIBITING THE INITIATION OF HERPES VIRAL DNA SYNTHESIS IN HOST CELLS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0611754-B1 | Dimerized thiourea derivatives, near-infrared absorbents comprising the same, and heat wave shielding materials comprising the same | JUJO PAPER CO LTD (JP) | 1998-04-22 | — | — | EP | disclosed |
| US-5723075-A | HEAT RESISTANT ABSORBERS WITH RESINS FOR SHIELDS | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0611754-A1 | Dimerized thiourea derivatives, near-infrared absorbents comprising the same, and heat wave shielding materials comprising the same | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |