SCHEMBL6578813

SCHEMBL6578813

CCCOC(=O)N(CCC)CCC.c1ncncn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
ALDH1A1 P00352 4/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 2/20 0.34
CHRM1 P11229 2/20 0.34
MAPK1 P28482 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRM3 P20309 1/20 0.34
CHRNA4 P43681 1/20 0.34
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
ESR1 P03372 1/20 0.33
SLC6A2 P23975 1/20 0.33
KDR P35968 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899761 0.88 CA12 (0.44) CA12CA2CA9ALDH1A1TP53
SCHEMBL5265758 0.82 ALDH1A1 (0.42) CA12CA9ALDH1A1TSHRMAPK1
SCHEMBL10087947 0.78 CA12 (0.46) CA12CA2CA9ALDH1A1TP53
SCHEMBL19018673 0.76 CA12 (0.48) CA12CA2CA9ALDH1A1TSHR
SCHEMBL8909554 0.76 ALDH1A1 (0.52) CA12CA2CA9ALDH1A1TSHR
SCHEMBL14005100 0.76 CA12 (0.41) CA12CA2CA9ALDH1A1TP53
Hydrochloric Acid SCHEMBL28190002 0.76 CA12 (0.44) CA12CA2CA9ALDH1A1TP53
SCHEMBL25275042 0.75 CA12 (0.42) CA12CA2CA9ALDH1A1TSHR
SCHEMBL14759196 0.75 NAAA (0.50) CA12CA2CA9ALDH1A1TP53
SCHEMBL14388860 0.75 CA12 (0.40) CA12CA2CA9ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930303-B1 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECH CORP (US) 2004-02-04 EP disclosed
EP-0933371-B1 N-halo acid amides CYTEC TECH CORP (US) 2003-04-09 EP disclosed
EP-0565774-B1 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECH CORP (US) 2001-03-28 EP disclosed
EP-0933371-A1 N-halo acid amides CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933370-A1 Tris-(2,2,6,6-tetramethyl-piperid-4-yl-aminocarbonyl)melamine CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933369-A1 Tris-(omega-haloacyl)melamines CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0930303-A2 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1999-07-21 EP disclosed
US-5571915-A Process for preparing amide derivatives from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1996-11-05 US disclosed
US-5405959-A Haloaminotraizines and acid halides CYTEC TECHNOLOGY CORP. (US) 1995-04-11 US disclosed
US-5288865-A Process for preparing amide derivatives from haloaminotriazines and acid halides AMERICAN CYANAMID COMPANY (US) 1994-02-22 US disclosed
EP-0565774-A2 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1993-10-20 EP disclosed
EP-0541966-A2 Process for preparing amide derivatives from halomines and acid halides AMERICAN CYANAMID COMPANY (US) 1993-05-19 EP disclosed