SCHEMBL8909554

SCHEMBL8909554

CCCCOC(=O)N(CCC)CCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
ATM Q13315 1/20 0.48
TSHR P16473 6/20 0.45
HPGD P15428 1/20 0.45
HCAR2 Q8TDS4 1/20 0.42
NAAA Q02083 1/20 0.42
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
CA2 P00918 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
EPHX1 P07099 1/20 0.39
MAPK1 P28482 2/20 0.39
DNM1 Q05193 1/20 0.39
LMNA P02545 1/20 0.39
ESR1 P03372 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1H2 P55055 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14759196 0.94 NAAA (0.50) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL25226358 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAAEPHX1
SCHEMBL14759435 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAAEPHX1
SCHEMBL25229297 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAAEPHX1
SCHEMBL65775 0.91 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL25226108 0.89 ALDH1A1 (0.50) ALDH1A1ATMTSHRHPGDHCAR2
Ammonia Solution, Strong SCHEMBL28649190 0.89 ALDH1A1 (0.50) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL25229268 0.88 NAAA (0.48) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL721996 0.88 NAAA (0.48) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL534600 0.88 NAAA (0.48) ALDH1A1ATMTSHRHPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
US-11291659-B2 P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD Fulcrum Therapeutics, Inc. (US) 2022-04-05 US disclosed
EP-2568019-B1 Inkjet ink JNC CORP (JP) 2015-09-02 EP disclosed
US-9040625-B2 Water/oil repellent composition, method for its production and article ASAHI GLASS COMPANY, LIMITED (JP) 2015-05-26 US disclosed
EP-2703466-A1 WATER-REPELLENT AND OIL-REPELLENT AGENT COMPOUND, MANUFACTURING METHOD THEREFOR, AND ARTICLE Asahi Glass Company, Limited (JP) 2014-03-05 EP disclosed
US-20140051797-A1 WATER/OIL REPELLENT COMPOSITION, METHOD FOR ITS PRODUCTION AND ARTICLE ASAHI GLASS COMPANY, LIMITED (JP) 2014-02-20 US disclosed
EP-2568019-A1 Inkjet ink JNC Corporation (JP) 2013-03-13 EP disclosed
EP-0575191-B1 Non-aqueous electrolyte solvent and battery containing this electrolyte MITSUI PETROCHEMICAL IND (JP) 1997-08-27 EP disclosed
US-5385794-A Lithium battery; carbamate and cyclic carbonate solvents MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1995-01-31 US disclosed
EP-0575191-A1 Non-aqueous electrolyte solvent and battery containing this electrolyte MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291659-B2 P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD ZFX, TBL1XR1, TRIM28 ALDH1A1 4699/4885ATM 2042/4885TSHR 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.