Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977901 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL6579112 | 0.77 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL6578834 | 0.76 | KDM4E (0.52) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL6581634 | 0.73 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL6579736 | 0.67 | KDM4E (0.53) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL9589798 | 0.67 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL10670471 | 0.65 | MEN1 (0.76) | ALDH1A1KDM4EHPGDHIF1AMAPT | |
| SCHEMBL7964597 | 0.65 | CNR2 (0.54) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL10674158 | 0.64 | MEN1 (0.59) | ALDH1A1KDM4EHPGDHIF1AMAPT | |
| SCHEMBL30323359 | 0.63 | NR1H2 (0.50) | ALDH1A1KDM4EGAAHPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |