Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977901 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL6578834 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL6579112 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL28825720 | 0.78 | NTRK1 (0.53) | ALDH1A1KDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL8001907 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EGAAHIF1ATP53 | |
| SCHEMBL6578836 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAHPGDHIF1A | |
| SCHEMBL28211409 | 0.70 | NTRK1 (0.56) | TP53SMN1; SMN2NPC1BRD4MAPT | |
| SCHEMBL19086664 | 0.70 | HIF1A (0.71) | ALDH1A1KDM4EGAAHIF1A | |
| SCHEMBL19086870 | 0.70 | NPC1 (0.53) | ALDH1A1KDM4EGAAHIF1ANPC1 | |
| SCHEMBL13598012 | 0.69 | NPC1 (0.67) | ALDH1A1KDM4EHPGDHIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |