Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CREB1 | P16220 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976008 | 0.86 | KDM4E (0.45) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL6581984 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6580908 | 0.78 | GAA (0.38) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6580910 | 0.78 | GAA (0.38) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL7977894 | 0.74 | VKORC1 (0.36) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7977898 | 0.74 | VKORC1 (0.36) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6581127 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL6582186 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL7999095 | 0.68 | ALDH1A1 (0.42) | ALDH1A1KDM4EPABPC1GAAHPGD | |
| SCHEMBL7977916 | 0.68 | HDAC6 (0.44) | ALDH1A1KDM4EKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |