Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 12/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 12/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.55 |
| ▸ | PTGIR | P43119 | 3/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.55 |
| ▸ | PTGFR | P43088 | 2/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 3/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100109 | 0.71 | PTGDR (1.00) | PTGDRTBXA2RPTGER3PTGER2PTGIR | |
| SCHEMBL1408220 | 0.70 | PDE2A (1.00) | PTGDRTBXA2RPTGER3PTGER2PTGIR | |
| SCHEMBL4100256 | 0.66 | PDE2A (0.78) | PTGDRTBXA2RPTGER3PTGER2PTGIR | |
| SCHEMBL14401183 | 0.64 | PTGDR (0.62) | PTGDRTBXA2RPTGER3PTGER2PTGIR | |
| SCHEMBL5778034 | 0.61 | TBXA2R (0.43) | PTGDRTBXA2RPTGER3PTGER2PTGIR | |
| SCHEMBL4681125 | 0.56 | SLC5A2 (0.45) | LMNAMAPT | |
| SCHEMBL25515855 | 0.55 | KDM4E (0.52) | IDO1LMNANR2F2HTTSMN1; SMN2 | |
| SCHEMBL20680299 | 0.54 | MAPT (0.42) | LMNASMN1; SMN2MAPT | |
| SCHEMBL11719377 | 0.53 | P2RX3 (0.54) | IDO1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL3890367 | 0.53 | KDM4E (0.44) | IDO1KDM4ECYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470107-A2 | FLUORO SUBSTITUTED CYCLOALKANOINDOLES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Merck Frosst Canada & Co. (CA) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003062200-A2 | FLUORO SUBSTITUTED CYCLOALKANOINDOLES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA & CO. (CA) | 2003-07-31 | — | — | WO | disclosed |