Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.38 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.38 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 4/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579542 | 0.89 | GCGR (0.35) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL6579539 | 0.85 | ITGB1 (0.35) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL1897805 | 0.83 | BACE1 (0.39) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL5751437 | 0.82 | ITGB1 (0.37) | ITGB1ITGA4MMEPPARA | |
| SCHEMBL5753208 | 0.78 | ITGB1 (0.38) | ITGB1ITGA4CNR2 | |
| SCHEMBL5751447 | 0.76 | CTSV (0.36) | ITGB1ITGA4CNR1CTSVCTSL | |
| SCHEMBL5750208 | 0.76 | CTSL (0.46) | ITGB1ITGA4CTSVCTSLCTSB | |
| SCHEMBL5751364 | 0.75 | BACE1 (0.41) | ITGB1ITGA4CTSVCTSLCTSB | |
| SCHEMBL5752027 | 0.75 | FFAR2 (0.37) | ITGB1ITGA4CTSVCTSLCTSB | |
| SCHEMBL5752124 | 0.75 | BACE1 (0.38) | CNR1CTSVCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |