Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 13/20 | 0.61 |
| ▸ | PLK3 | Q9H4B4 | 7/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581823 | 0.90 | PLK1 (0.58) | PLK1PLK3TRPV1KDM4EABCG2 | |
| SCHEMBL6577993 | 0.90 | PLK1 (0.61) | PLK1PLK3TRPV1ABCG2 | |
| SCHEMBL6580254 | 0.87 | NR1H4 (0.53) | PLK1PLK3TRPV1KDM4EABCG2 | |
| SCHEMBL6577703 | 0.84 | PLK1 (0.64) | PLK1 | |
| SCHEMBL28418450 | 0.81 | PLK1 (0.60) | PLK1 | |
| SCHEMBL6580460 | 0.81 | NPC1 (0.48) | KDM4E | |
| SCHEMBL3415084 | 0.81 | NR1H4 (0.62) | PLK1PLK3 | |
| SCHEMBL1464667 | 0.81 | PLK1 (0.90) | PLK1PLK3TRPV1 | |
| SCHEMBL23657651 | 0.80 | TRPV1 (0.68) | PLK1PLK3TRPV1 | |
| SCHEMBL6579964 | 0.80 | NPC1 (0.51) | TRPV1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |