Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | WDR5 | P61964 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299507 | 0.81 | CA1 (0.56) | CA1CA2CA12CA7CA9 | |
| Cyanate SCHEMBL28803587 | 0.80 | CA1 (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8218934 | 0.80 | LOXL2 (0.47) | CA1CA2CA12CA7CA9 | |
| Water SCHEMBL22720573 | 0.79 | CA1 (0.76) | CA1CA2CA12CA7CA9 | |
| SCHEMBL15976681 | 0.79 | HPGD (0.59) | CA2TDP1MAPTALDH1A1KMT2A | |
| SCHEMBL6575703 | 0.78 | CA1 (0.61) | CA1CA2CA12CA7CA9 | |
| SCHEMBL944296 | 0.78 | CA1 (0.61) | CA1CA2CA12CA7CA9 | |
| SCHEMBL25080824 | 0.77 | KMT2A (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13496844 | 0.77 | CA2 (0.39) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13496845 | 0.77 | CA2 (0.39) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362382-A1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL DRUG DEVELOPMENT, LLC | 2016-12-15 | — | — | US | disclosed |
| US-20160362382-A1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL DRUG DEVELOPMENT, LLC | 2016-12-15 | — | — | US | disclosed |
| US-9464059-B2 | Benzamide derivatives | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2016-10-11 | — | — | US | disclosed |
| US-9464059-B2 | Benzamide derivatives | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150284336-A1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL DRUG DEVELOPMENT, LLC | 2015-10-08 | — | — | US | disclosed |
| US-9125901-B2 | 4-(benzimidazol-2-ylamino)benzamide derivatives and salts or solvates thereof | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2015-09-08 | — | — | US | disclosed |
| EP-2445345-B1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL GENOMICS RES INST (US) | 2014-08-27 | — | — | EP | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120142922-A1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2012-06-07 | — | — | US | disclosed |
| EP-1120435-B1 | APPARATUS AND METHOD FOR PRODUCING RESIN | TEIJIN LTD (JP) | 2004-05-06 | — | — | EP | disclosed |
| US-6562936-B1 | Resin excellent in hydrolysis and heat stability such as a reduction in molecular weight at the time of molding and color retention and moldability such as releasability and transferability, rarely experiences residence deterioration | TEIJIN LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-6509435-B1 | Heat resistance, stability; moldings | TEIJIN LIMITED (JP) | 2003-01-21 | — | — | US | disclosed |
| CN-1371399-A | Polycarbonate, process for producing the same and molded article thereof | TEIJIN LTD (JP) | 2002-09-25 | — | — | CN | disclosed |
| EP-1191049-A1 | POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF | TEIJIN LIMITED (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-1120435-A1 | APPARATUS AND METHOD FOR PRODUCING RESIN | TEIJIN LIMITED (JP) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142922-A1 | BENZAMIDE DERIVATIVES | BRDT, BRD3, BRD2 | CA1 4581/4885CA2 3907/4885CA12 4057/4885 |
| US-20150284336-A1 | BENZAMIDE DERIVATIVES | BRDT, BRD3, BRD2 | CA1 4581/4885CA2 3907/4885CA12 4057/4885 |
| US-20160362382-A1 | BENZAMIDE DERIVATIVES | BRDT, BRD3, BRD2 | CA1 4581/4885CA2 3907/4885CA12 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.