Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577021 | 0.84 | PLA2G4B (0.39) | NPC1RAB9ATSHRMAPK10ALDH1A1 | |
| SCHEMBL6579800 | 0.78 | TSHR (0.44) | NPC1RAB9ATSHRMAPK10ALDH1A1 | |
| SCHEMBL6579467 | 0.74 | SMN1; SMN2 (0.45) | TSHRMAPK10ALDH1A1TP53CYP1A2 | |
| SCHEMBL15903502 | 0.74 | TSHR (0.51) | NPC1RAB9ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL6578894 | 0.71 | SMN1; SMN2 (0.45) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL14252251 | 0.70 | TSHR (0.65) | NPC1RAB9ATSHRALDH1A1TP53 | |
| SCHEMBL6579151 | 0.69 | SMN1; SMN2 (0.43) | ALDH1A1TP53L3MBTL1TDP1ESR1 | |
| SCHEMBL6579573 | 0.69 | TSHR (0.48) | NPC1RAB9ATSHRMAPK10ALDH1A1 | |
| SCHEMBL6579134 | 0.69 | CYP1A2 (0.41) | NPC1RAB9AMAPK10ALDH1A1TP53 | |
| SCHEMBL6581436 | 0.69 | LMNA (0.44) | NPC1RAB9ATSHRMAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |