Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581436 | 0.91 | LMNA (0.44) | TSHRMAPK10HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL6579134 | 0.91 | CYP1A2 (0.41) | MAPK10HSD17B10CYP1A2USP2CYP2D6 | |
| SCHEMBL6579467 | 0.84 | SMN1; SMN2 (0.45) | TSHRMAPK10CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL6579783 | 0.84 | TSHR (0.48) | TSHRMAPK10HSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL6579803 | 0.82 | ALDH1A1 (0.40) | TSHRHSD17B10ALDH1A1GAAMEN1 | |
| SCHEMBL6576926 | 0.79 | CYP1A2 (0.38) | TSHRHSD17B10CYP1A2CYP2D6SCN1A | |
| SCHEMBL7998601 | 0.78 | TSHR (0.39) | TSHRMAPK10HSD17B10CYP1A2USP2 | |
| SCHEMBL6579572 | 0.78 | ALDH1A1 (0.43) | TSHRHSD17B10CYP1A2CYP2D6SCN1A | |
| SCHEMBL6579039 | 0.78 | ALDH1A1 (0.43) | TSHRHSD17B10CYP1A2CYP2D6SCN1A | |
| SCHEMBL6579965 | 0.78 | NPC1 (0.45) | TSHRMAPK10CYP1A2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |