Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577705 | 0.95 | NR1H4 (0.78) | NR1H4MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL6579950 | 0.90 | NPC1 (0.73) | NR1H4MAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL6581896 | 0.85 | NR1H4 (0.72) | NR1H4MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6580034 | 0.85 | KCNK9 (0.72) | TP53SMN1; SMN2RXFP1NPC1RAB9A | |
| SCHEMBL8108301 | 0.84 | NR1H4 (0.78) | NR1H4MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8119505 | 0.83 | NR1H4 (0.83) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6165569 | 0.83 | NR1H4 (0.83) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6580176 | 0.82 | NR1H4 (0.66) | NR1H4MAPTTP53SMN1; SMN2RXFP1 | |
| SCHEMBL6580184 | 0.82 | NR1H4 (0.58) | NR1H4MAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL196100 | 0.82 | NPC1 (0.75) | NR1H4MAPTTP53SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |