Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | TP53 | P04637 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580034 | 0.94 | KCNK9 (0.72) | KCNK9NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6580059 | 0.90 | NR1H4 (0.66) | KCNK9NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6580464 | 0.86 | NR1H4 (0.58) | KCNK9NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6579969 | 0.84 | KMT2A (0.58) | KCNK9NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6580081 | 0.83 | NLRP3 (0.69) | RAB9ATP53SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6580260 | 0.82 | TRPV1 (0.56) | KCNK9NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6579950 | 0.81 | NPC1 (0.73) | NPC1RAB9ATP53SMN1; SMN2KMT2A | |
| SCHEMBL6580184 | 0.81 | NR1H4 (0.58) | KCNK9NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL31542000 | 0.81 | KCNK9 (0.81) | KCNK9NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6580158 | 0.81 | KMT2A (0.54) | KCNK9NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |