Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.45 |
| ▸ | PARG | Q86W56 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577807 | 0.87 | HTR6 (0.39) | HTR6PARGPTGDR2 | |
| SCHEMBL6579484 | 0.86 | HTR6 (0.47) | HTR6PARGPTGDR2 | |
| SCHEMBL6577381 | 0.86 | HTR6 (0.48) | HTR6PARG | |
| SCHEMBL6580232 | 0.81 | HTR6 (0.48) | HTR6PTGDR2 | |
| SCHEMBL6575514 | 0.81 | HTR6 (0.45) | HTR6PTGDR2PTGDR | |
| Hydrochloric Acid SCHEMBL6577886 | 0.80 | HTR6 (0.44) | HTR6PTGDR2PTGDR | |
| SCHEMBL6577305 | 0.79 | HTR6 (0.44) | HTR6PARGPTGDR2PTGDR | |
| Hydrochloric Acid SCHEMBL6577805 | 0.78 | HTR6 (0.43) | HTR6PARGPTGDR2PTGDR | |
| SCHEMBL6577278 | 0.75 | SPR (0.45) | HTR6PARG | |
| SCHEMBL7170076 | 0.74 | HTR6 (0.39) | HTR6PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411925-A1 | 5-ARYLSULFONYL INDOLES HAVING 5-HT6 RECEPTOR AFFINITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011284-A1 | 5-ARYLSULFONYL INDOLES HAVING 5-HT6 RECEPTOR AFFINITY | PHARMACIA & UPJOHN COMPANY (US) | 2003-02-13 | — | — | WO | disclosed |