Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580243 | 1.00 | CYP1A2 (0.46) | CYP1A2CYP2C19TGM2ALDH1A1KDM4E | |
| SCHEMBL10961137 | 0.83 | SLC5A1 (0.44) | CYP1A2CYP2C19TGM2ALDH1A1KDM4E | |
| SCHEMBL10959710 | 0.83 | KMT2A (0.49) | CYP1A2CYP2C19ALDH1A1LMNATSHR | |
| SCHEMBL6580053 | 0.83 | ALOX5 (0.41) | CYP1A2CYP2C19TSHRALOX5PTGES2 | |
| SCHEMBL6580049 | 0.83 | ALOX5 (0.41) | CYP1A2CYP2C19TSHRALOX5PTGES2 | |
| SCHEMBL6581989 | 0.76 | TGM2 (0.51) | TGM2ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL6577327 | 0.75 | HPGD (0.54) | ALDH1A1LMNATSHRFEN1MEN1 | |
| SCHEMBL23780328 | 0.75 | NPC1 (0.47) | CYP2C19ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL11271744 | 0.74 | HPGD (0.53) | ALDH1A1LMNATSHRFEN1MEN1 | |
| SCHEMBL6357752 | 0.71 | P2RX7 (0.67) | CYP1A2CYP2C19TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |