Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.65 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580649 | 0.89 | OPRM1 (0.62) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL9057503 | 0.83 | OPRM1 (0.91) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL9057334 | 0.83 | OPRM1 (0.91) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL1831981 | 0.82 | OPRM1 (0.58) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL9058026 | 0.80 | OPRM1 (0.64) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL9057719 | 0.80 | OPRM1 (0.64) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL3895786 | 0.80 | CHRM1 (0.92) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL7961184 | 0.80 | OPRM1 (1.00) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL8677294 | 0.80 | CHRM1 (0.69) | OPRM1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL4636037 | 0.79 | CHRM1 (1.00) | OPRM1CHRM1CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1221443-B1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |