Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MLNR | O43193 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580272 | 0.89 | OPRM1 (0.66) | OPRM1CHRM2CHRM1OPRK1CHRM4 | |
| SCHEMBL1831981 | 0.80 | OPRM1 (0.58) | OPRM1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL1831985 | 0.79 | OPRM1 (0.53) | OPRM1OPRK1OPRL1PMP22OPRD1 | |
| SCHEMBL22716742 | 0.77 | HSD11B1 (0.54) | OPRM1CHRM2CHRM1OPRK1CHRM4 | |
| SCHEMBL319049 | 0.77 | CHRM1 (0.70) | OPRM1CHRM2CHRM1OPRK1CHRM4 | |
| SCHEMBL7961184 | 0.76 | OPRM1 (1.00) | OPRM1OPRK1OPRL1OPRD1PLD1 | |
| SCHEMBL4084782 | 0.74 | CHRM1 (0.76) | OPRM1CHRM2CHRM1OPRK1CHRM4 | |
| SCHEMBL31285882 | 0.74 | CHRM1 (0.58) | OPRM1CHRM2CHRM1OPRK1CHRM4 | |
| SCHEMBL22605476 | 0.74 | CHRM1 (0.58) | OPRM1CHRM2CHRM1OPRK1CHRM4 | |
| SCHEMBL3142425 | 0.74 | CHRM1 (0.81) | OPRM1CHRM2CHRM1OPRK1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1221443-B1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |