SCHEMBL6580294

SCHEMBL6580294

C=CCOCc1c(C)cccc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
SLC22A12 Q96S37 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CXCR5 P32302 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
CYP2A6 P11509 1/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18184988 0.81 TSHR (0.46) ALDH1A1KDM4EHSD17B10MEN1KMT2A
SCHEMBL865078 0.80 CYP1A2 (0.41) ALDH1A1SLC22A12CYP3A4CYP1A2CYP2D6
SCHEMBL18092255 0.80 KMT2A (0.33) ALDH1A1MEN1KMT2AOPRM1OPRD1
O-Xylene SCHEMBL2065413 0.79 TSHR (0.48) ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5597285 0.78 ALDH1A1 (0.45) ALDH1A1CYP3A4ADRA2AADRA2BADRA2C
SCHEMBL2091194 0.77 SLC22A12 (0.36) ALDH1A1SLC22A12CYP3A4CYP1A2CYP2D6
SCHEMBL7097064 0.77 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AHSP90AA1ATM
SCHEMBL15610593 0.75 CYP3A4 (0.38) ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5611733 0.74 ALDH1A1 (0.37) ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL17055828 0.74 SLC22A12 (0.37) ALDH1A1SLC22A12CYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1080084-B1 PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS DOW GLOBAL TECHNOLOGIES INC (US) 2004-05-06 EP claimed
CN-1303382-A Epoxidation process for aryl allyl ethers DOW CHEMICAL CO (US) 2001-07-11 CN claimed
CN-117700387-A Rockwell-like alcohol compound, intermediate, preparation method and application 深圳湾实验室 2024-03-15 CN disclosed