SCHEMBL5597285

SCHEMBL5597285

C=CCOCc1ccccc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CDK4 P11802 2/20 0.41
CCND1 P24385 2/20 0.41
TAAR1 Q96RJ0 1/20 0.39
MAOB P27338 1/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
CHRM3 P20309 1/20 0.37
CCNB2 O95067 1/20 0.37
CDK1 P06493 1/20 0.37
CCNB1 P14635 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
CYP2A13 Q16696 1/20 0.36
CYP3A4 P08684 1/20 0.35
SLC5A1 P13866 1/20 0.35
SLC5A2 P31639 1/20 0.35
CHRM2 P08172 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11698533 0.86 CYP3A4 (0.41) ALDH1A1CYP3A4MAPT
SCHEMBL7097064 0.82 ALDH1A1 (0.38) ALDH1A1SLC5A1SLC5A2
O-Xylene SCHEMBL2065413 0.81 TSHR (0.48) ALDH1A1CYP3A4MAPT
SCHEMBL4315585 0.81 TAAR1 (0.50) ALDH1A1CDK4CCND1TAAR1MAOB
SCHEMBL14952785 0.81 CDK4 (0.47) ALDH1A1CDK4CCND1TAAR1MAOB
SCHEMBL12822006 0.80 ALDH1A1 (0.43) ALDH1A1CYP3A4MAPT
SCHEMBL11011645 0.78 GABRA1 (0.41) ALDH1A1ADRA2AADRA2BADRA2CCYP3A4
SCHEMBL6580294 0.78 ALDH1A1 (0.36) ALDH1A1ADRA2AADRA2BADRA2CCYP3A4
SCHEMBL18092263 0.78 ALDH1A1 (0.37) ALDH1A1MAPT
SCHEMBL16949972 0.78 IDO1 (0.55) ALDH1A1TAAR1CHRM3CHRM2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878781-B2 Poly(arylene ether)-containing thermoset composition in powder form, method for the preparation thereof, and articles derived therefrom GENERAL ELECTRIC (US) 2005-04-12 US claimed
JP-2004526030-A 2004-08-26 JP claimed
US-6770107-B2 CURABLE THERMOPLASTIC ELASTOMERS COMPRISING POLYPHENYL ETHERS, DIAMOND, CARBIDE OR NITRIDE PARTICLES, ACRYLIC AND ALLYL HOMOPOLYMERS, MOLDED TO FORM CUTTING OR GRINDING TOOLS HAVING WEAR RESISTANCE GENERAL ELECTRIC COMPANY 2004-08-03 US claimed
EP-1373409-A1 ABRASIVE-FILLED THERMOSET COMPOSITION AND ITS PREPARATION, AND ABRASIVE-FILLED ARTICLES AND THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2004-01-02 EP claimed
EP-1373410-A1 POLY(ARYLENE ETHER)-CONTAINING THERMOSET COMPOSITION IN POWDER FORM, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2004-01-02 EP claimed
US-20030153641-A1 Curable thermoplastic elastomers comprising polyphenyl ethers, diamond, carbide or nitride particles, acrylic and allyl homopolymers, molded to form cutting or grinding tools having wear resistance SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2003-08-14 US claimed
US-6593391-B2 Polyphenylene ether blend GENERAL ELECTRIC COMPANY 2003-07-15 US claimed
US-20030018116-A1 Abrasive-filled thermoset composition and its preparation, and abrasive-filled articles and their preparation DIAMOND INNOVATIONS, INC. 2003-01-23 US claimed
US-20020173597-A1 Poly(arylene ether)-containing thermoset composition in powder form, method for the preparation thereof, and articles derived therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-11-21 US claimed
WO-2002077102-A1 ABRASIVE-FILLED THERMOSET COMPOSITION AND ITS PREPARATION, AND ABRASIVE-FILLED ARTICLES AND THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2002-10-03 WO claimed
WO-2002077103-A1 POLY(ARYLENE ETHER)-CONTAINING THERMOSET COMPOSITION IN POWDER FORM, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-10-03 WO claimed
WO-2021183340-A1 RADIATION CURED COPOLYMERS OF DICARBONYL SUBSTITUTED-L-ALKENES AND ELECTRON RICH COMONOMERS SIRRUS, INC. (US) 2021-09-16 WO disclosed
EP-1373410-B1 POLY(ARYLENE ETHER)-CONTAINING THERMOSET COMPOSITION IN POWDER FORM, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GEN ELECTRIC (US) 2007-01-24 EP disclosed
EP-1373409-B1 ABRASIVE-FILLED THERMOSET COMPOSITION AND ITS PREPARATION, AND ABRASIVE-FILLED ARTICLES AND THEIR PREPARATION GEN ELECTRIC (US) 2005-06-15 EP disclosed
US-6878781-B2 Poly(arylene ether)-containing thermoset composition in powder form, method for the preparation thereof, and articles derived therefrom GENERAL ELECTRIC (US) 2005-04-12 US disclosed
WO-1999019374-A1 RESINS FROM N-ALKENYL AMIDES AND ALLYLIC MONOMERS ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1999-04-22 WO disclosed
EP-0909787-A1 Intercalates and exfoliates formed with monomers, oligomers and/or copolymers and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1999-04-21 EP disclosed
WO-1999006452-A1 PROCESS FOR MAKING HYDROXY-FUNCTIONAL ACRYLIC RESINS HAVING LOW RESIDUAL ALLYL MONOMER CONTENT ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1999-02-11 WO disclosed
US-5849830-A Intercalates and exfoliates formed with N-alkenyl amides and/or acrylate-functional pyrrolidone and allylic monomers, oligomers and copolymers and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1998-12-15 US disclosed
EP-0502372-A1 4-tert-Alkyl-2-Methylbenzaldehydedialkylacetals BASF Aktiengesellschaft (DE) 1992-09-09 EP disclosed