Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577988 | 0.81 | KDM4E (0.31) | KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7890511 | 0.80 | HRH3 (0.39) | KMT2AHRH3ALDH1A1NPSR1MEN1 | |
| SCHEMBL6580294 | 0.80 | ALDH1A1 (0.36) | KMT2AALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL8997706 | 0.77 | HRH3 (0.34) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL26361501 | 0.76 | MEN1 (0.35) | KMT2AALDH1A1MEN1POLB | |
| SCHEMBL18092263 | 0.76 | ALDH1A1 (0.37) | KMT2ASMN1; SMN2ALDH1A1NPSR1MEN1 | |
| SCHEMBL4795602 | 0.75 | ALDH1A1 (0.42) | KMT2AALDH1A1NPSR1MEN1POLB | |
| SCHEMBL14219119 | 0.74 | HPGD (0.41) | KMT2AALDH1A1MEN1 | |
| SCHEMBL5702537 | 0.74 | HRH3 (0.35) | KMT2ASMN1; SMN2HRH3ALDH1A1MEN1 | |
| SCHEMBL29083597 | 0.72 | HRH3 (0.34) | HRH3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072875-B1 | ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-3072875-B1 | ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9701605-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701605-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701605-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-07-11 | — | — | US | disclosed |
| CN-106008178-A | Organoleptic compounds | 国际香料和香精公司 | 2016-10-12 | — | — | CN | disclosed |
| US-20160280620-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2016-09-29 | — | — | US | disclosed |
| US-20160280620-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2016-09-29 | — | — | US | disclosed |
| EP-3072875-A1 | ORGANOLEPTIC COMPOUNDS | Belko, Robert P. (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-3072875-A1 | ORGANOLEPTIC COMPOUNDS | Belko, Robert P. (US) | 2016-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280620-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | TRPA1, TRPV1, TRPV5 | KMT2A 1374/4885SMN1; SMN2 4046/4885HRH3 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.