Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435546 | 0.75 | KMT2A (0.46) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL6585617 | 0.74 | CSNK2B (0.38) | DYRK1AHDAC1HDAC6HTR2AHTR2C | |
| SCHEMBL5421535 | 0.74 | HSD17B10 (0.52) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL7326732 | 0.71 | HSD17B10 (0.52) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL7001177 | 0.70 | ADRB2 (0.44) | POLLBCHEACHECDK4CCND1 | |
| SCHEMBL8446330 | 0.69 | CYP3A4 (0.59) | CDK4CCND1HDAC1HDAC6 | |
| SCHEMBL8444298 | 0.69 | CYP3A4 (0.59) | CDK4CCND1HDAC1HDAC6 | |
| SCHEMBL8446837 | 0.69 | CYP3A4 (0.59) | CDK4CCND1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL6582902 | 0.68 | CYP3A4 (0.58) | CDK4CCND1HDAC1HDAC6 | |
| 4,8-Dihydroxy-1-Tetralone SCHEMBL30966482 | 0.64 | POLL (0.62) | POLLHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424337-A1 | 4-hydroxy derivatives of 5,6,9,10-tetrahydro-10-((2-methyl-1h-imidazol-1-yl)methyl)-4h-pyrido-(3,2,1-jk)-carbazol-11(8h)-one | Solvay Pharmaceuticals GmbH (DE) | 2004-06-02 | — | — | EP | disclosed |
| EP-1424337-A1 | 4-hydroxy derivatives of 5,6,9,10-tetrahydro-10-((2-methyl-1h-imidazol-1-yl)methyl)-4h-pyrido-(3,2,1-jk)-carbazol-11(8h)-one | Solvay Pharmaceuticals GmbH (DE) | 2004-06-02 | — | — | EP | disclosed |