Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581093 | 1.00 | PTGES (0.44) | PTGESMTNR1AHDAC3HDAC4HDAC1 | |
| SCHEMBL6581090 | 1.00 | PTGES (0.44) | PTGESMTNR1AHDAC3HDAC4HDAC1 | |
| SCHEMBL7964637 | 0.93 | PTGES (0.42) | PTGESMTNR1AHDAC3HDAC4HDAC1 | |
| SCHEMBL7964629 | 0.93 | PTGES (0.42) | PTGESMTNR1AHDAC3HDAC4HDAC1 | |
| SCHEMBL7964631 | 0.93 | PTGES (0.42) | PTGESMTNR1AHDAC3HDAC4HDAC1 | |
| SCHEMBL6577205 | 0.83 | ALOX5 (0.44) | ALOX5BCHEACHEKDM1AMEN1 | |
| SCHEMBL6577201 | 0.83 | ALOX5 (0.44) | ALOX5BCHEACHEKDM1AMEN1 | |
| SCHEMBL6581043 | 0.80 | BCHE (0.44) | BCHEACHEMEN1GAAKMT2A | |
| SCHEMBL6581046 | 0.80 | BCHE (0.44) | BCHEACHEMEN1GAAKMT2A | |
| SCHEMBL7974960 | 0.76 | ALDH1A1 (0.47) | ALOX5BCHEACHEKDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |