Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA5A | P35218 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581254 | 0.89 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1KDM4EPPARA | |
| SCHEMBL6971349 | 0.85 | MEN1 (0.53) | KMT2AMEN1CISD1HPGD | |
| SCHEMBL6585566 | 0.84 | ALDH1A1 (0.54) | KMT2AMEN1CISD1ALDH1A1KDM4E | |
| SCHEMBL6971353 | 0.83 | MEN1 (0.44) | KMT2AMEN1CISD1ALDH1A1KDM4E | |
| SCHEMBL6582223 | 0.83 | TRPA1 (0.48) | ALDH1A1KDM4EPPARAPPARGCA2 | |
| SCHEMBL6582227 | 0.83 | TRPA1 (0.48) | ALDH1A1KDM4EPPARAPPARGCA2 | |
| SCHEMBL8188195 | 0.83 | MEN1 (0.55) | KMT2AMEN1CISD1ALDH1A1KDM4E | |
| SCHEMBL8186829 | 0.79 | MEN1 (0.52) | KMT2AMEN1CISD1ALDH1A1KDM4E | |
| SCHEMBL6586658 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1PPARAPPARG | |
| SCHEMBL8482892 | 0.79 | CA2 (0.57) | ALDH1A1KDM4ECA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |