Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 5/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606264 | 0.72 | ADORA3 (0.45) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| Biphenyl SCHEMBL27882235 | 0.70 | TDP1 (0.89) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL29600941 | 0.70 | ADORA3 (0.53) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4605578 | 0.70 | ADORA3 (0.42) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5229508 | 0.69 | ALDH1A1 (0.47) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL5228972 | 0.69 | FGFR1 (0.50) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL5901698 | 0.69 | FGFR1 (0.50) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL5965259 | 0.69 | FGFR1 (0.50) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL11768019 | 0.69 | TDP1 (0.49) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL476278 | 0.68 | TDP1 (0.79) | TDP1ALDH1A1GLATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737680-B1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-5679699-A | ANTIISCHEMIC AGENTS, HEART RATE LOWERING AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1997-10-21 | — | — | US | disclosed |
| EP-0737680-A1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1996-10-16 | — | — | EP | disclosed |
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |