Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.61 |
| ▸ | DRD2 | P14416 | 9/20 | 0.50 |
| ▸ | DRD4 | P21917 | 7/20 | 0.50 |
| ▸ | DRD3 | P35462 | 8/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726820 | 0.87 | ESR2 (0.46) | ESR1ESR2DRD2DRD4DRD3 | |
| SCHEMBL29659975 | 0.82 | HTR2C (0.41) | ESR1ESR2DRD4ARMEN1 | |
| SCHEMBL10841091 | 0.82 | HTR2C (0.41) | ESR1ESR2DRD4ARMEN1 | |
| SCHEMBL19289729 | 0.81 | LMNA (0.49) | ESR1ESR2DRD2DRD4DRD3 | |
| SCHEMBL20156702 | 0.81 | LMNA (0.49) | ESR1ESR2DRD2DRD4DRD3 | |
| SCHEMBL4133012 | 0.80 | AR (0.40) | ESR1ESR2DRD2ARLMNA | |
| SCHEMBL30499354 | 0.80 | AR (0.40) | ESR1ESR2DRD2ARLMNA | |
| SCHEMBL21243002 | 0.80 | AR (0.40) | ESR1ESR2DRD2ARLMNA | |
| SCHEMBL13091374 | 0.80 | AR (0.40) | ESR1ESR2DRD2ARLMNA | |
| SCHEMBL16585592 | 0.79 | PNMT (0.45) | ESR1ESR2ARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988106-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-109988106-A | The aminated compounds for inhibiting SSAO/VAP-1 and its application in medicine | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| EP-0867432-B1 | Fused N-heterocyclic compounds substituted with benzyloxy, process for their preparation and their use as bradykinin receptor antagonists | AVENTIS PHARMA GMBH (DE) | 2004-06-09 | — | — | EP | disclosed |
| EP-0867432-A2 | Fused N-heterocyclic compounds substituted with benzyloxy, process for their preparation and their use as bradykinin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-30 | — | — | EP | disclosed |