Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499354 | 1.00 | AR (0.40) | ARESR1ESR2GAAMGAM | |
| SCHEMBL13091374 | 1.00 | AR (0.40) | ARESR1ESR2GAAMGAM | |
| SCHEMBL21243002 | 1.00 | AR (0.40) | ARESR1ESR2GAAMGAM | |
| SCHEMBL24359176 | 0.87 | HTR5A (0.39) | ARGAAHTR5ASRD5A1PARP10 | |
| SCHEMBL10991106 | 0.87 | HTR5A (0.39) | ARGAAHTR5ASRD5A1PARP10 | |
| SCHEMBL7922397 | 0.81 | GAA (0.47) | ARGAAMGAMSIMGAM2 | |
| SCHEMBL30101714 | 0.81 | GAA (0.47) | ARGAAMGAMSIMGAM2 | |
| SCHEMBL6581441 | 0.80 | ESR1 (0.61) | ARESR1ESR2DRD2LMNA | |
| SCHEMBL16585592 | 0.80 | PNMT (0.45) | ARESR1ESR2SRD5A1PARP10 | |
| SCHEMBL9394761 | 0.80 | AR (0.40) | ARESR1ESR2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141252-A | A kind of method that hydrotalcite-like materials are catalyzed nitrogen-containing heterocycle compound oxidative dehydrogenation | 常州大学 | 2017-09-08 | — | — | CN | claimed |
| US-9321730-B2 | Method of making and administering quinoline derivatives as anti-cancer agents | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2016-04-26 | — | — | US | claimed |
| EP-2188259-B1 | QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS | UNIV HONG KONG POLYTECHNIC (CN) | 2013-11-06 | — | — | EP | claimed |
| US-20090054482-A1 | Method of making and administering quinoline derivatives as anti-cancer agents | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-02-26 | — | — | US | claimed |
| CN-116272943-B | Carbon-based nonmetallic catalyst and preparation method and application thereof | 遵义医科大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-116272943-A | Carbon-based nonmetallic catalyst and preparation method and application thereof | 遵义医科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-113717098-B | Method for synthesizing tetrahydroquinoline compound by selectively catalyzing and hydrogenating quinoline compound with non-hydrogen | 延安大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113264876-B | Method for selectively catalyzing and hydrogenating aromatic heterocyclic compounds by non-hydrogen participation | 延安大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113717098-A | Method for synthesizing tetrahydroquinoline compound by selectively catalyzing and hydrogenating quinoline compound with non-hydrogen | 延安大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-113264876-A | Method for selectively catalyzing and hydrogenating aromatic heterocyclic compounds by non-hydrogen participation | 延安大学 | 2021-08-17 | — | — | CN | disclosed |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2021-03-23 | — | — | US | disclosed |
| CN-106831565-B | The restoring method of benzo aromatic aza cyclics | 三峡大学 | 2019-11-08 | — | — | CN | disclosed |
| US-20090054482-A1 | Method of making and administering quinoline derivatives as anti-cancer agents | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-02-26 | — | — | US | disclosed |
| US-20090054482-A1 | Method of making and administering quinoline derivatives as anti-cancer agents | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-02-26 | — | — | US | disclosed |
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |
| US-4014877-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1977-03-29 | — | — | US | disclosed |
| US-4001243-A | ANTI-MICROBIAL | RIKER LABORATORIES, INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3985882-A | ADMISTERING | RIKER LABORATORIES, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3969463-A | MICROBIOCIDE | RIKER LABORATORIES, INC. (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | SBK1, SIK1, SIK2 | AR 1473/4885ESR1 3346/4885ESR2 4480/4885 |
| US-20090054482-A1 | Method of making and administering quinoline derivatives as anti-cancer agents | HCCS, GLS2, NQO1 | AR 4166/4885ESR1 4245/4885ESR2 3615/4885 |
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | AR 4868/4885ESR1 4661/4885ESR2 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.