Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579509 | 0.93 | ALDH1A1 (0.44) | ALDH1A1LMNAL3MBTL1KDM4EHPGD | |
| SCHEMBL8307546 | 0.89 | PPARA (0.33) | EGFRCA1CA2ALDH1A1LMNA | |
| SCHEMBL6579875 | 0.84 | KMT2A (0.41) | EGFRCA1CA2CA12CA7 | |
| SCHEMBL6579028 | 0.80 | CA12 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6579175 | 0.79 | SMN1; SMN2 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6581198 | 0.76 | MMP1 (0.43) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6581205 | 0.76 | MMP1 (0.43) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6582050 | 0.76 | PLK1 (0.37) | EGFRALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL6578819 | 0.75 | TDP1 (0.41) | ALDH1A1LMNAHPGDTDP1MAPT | |
| SCHEMBL6581292 | 0.75 | EGFR (0.43) | EGFRCA1CA2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |