Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581444 | 0.89 | EGFR (0.39) | ALDH1A1LMNACA1CA2MAPT | |
| SCHEMBL6579509 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHTTMAPTTDP1 | |
| SCHEMBL27474525 | 0.77 | TAAR1 (0.38) | PPARAALDH1A1LMNAACHEEGFR | |
| SCHEMBL27489939 | 0.76 | KMT2A (0.33) | PPARAALDH1A1HTTEGFRLCK | |
| SCHEMBL6579875 | 0.73 | KMT2A (0.41) | ALDH1A1CA1CA2MAPTEGFR | |
| SCHEMBL27475381 | 0.72 | MCHR1 (0.40) | ALDH1A1LMNAHTTFFAR1MAPT | |
| SCHEMBL27489936 | 0.72 | LTB4R (0.39) | ALDH1A1LMNAHTTMAOBKMT2A | |
| SCHEMBL27490654 | 0.71 | CA12 (0.32) | ALDH1A1CA1CA2MAPTTDP1 | |
| SCHEMBL27511940 | 0.70 | ACHE (0.40) | ACHE | |
| SCHEMBL6577164 | 0.70 | MAPT (0.47) | ALDH1A1LMNAHTTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |