Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.51 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462768 | 0.85 | GABBR2 (0.49) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL14580268 | 0.84 | MEN1 (0.45) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL17755252 | 0.84 | FFAR1 (0.52) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL31462584 | 0.84 | GABBR2 (0.47) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL11085231 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL656899 | 0.80 | GABBR2 (0.47) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL7524253 | 0.79 | MME (0.40) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL11429015 | 0.79 | EEF2K (0.41) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL16971145 | 0.79 | CYP1A2 (0.49) | GABBR2GABBR1LMNACYP2C9MEN1 | |
| SCHEMBL658019 | 0.79 | EEF2K (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | disclosed |