Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581687 | 1.00 | SIGMAR1 (0.42) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| Maleic Acid SCHEMBL6583290 | 0.86 | HTR7 (0.43) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| Fumaric Acid SCHEMBL6580691 | 0.86 | HTR7 (0.43) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| Fumaric Acid SCHEMBL6581608 | 0.86 | HTR7 (0.43) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| SCHEMBL6581745 | 0.81 | SIGMAR1 (0.43) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| SCHEMBL6217205 | 0.77 | MEN1 (0.46) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| SCHEMBL6217147 | 0.77 | MEN1 (0.46) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| SCHEMBL6219114 | 0.75 | MEN1 (0.47) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| SCHEMBL6216542 | 0.75 | MEN1 (0.47) | SIGMAR1HTR7MEN1KMT2AHTR1A | |
| Cadaverine Tartrate SCHEMBL6218477 | 0.74 | MEN1 (0.42) | SIGMAR1HTR7MEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307441-B1 | 1,3-DIOXOLANES WITH ANTITUSSIVE ACTIVITY | DOMPE SPA (IT) | 2004-05-06 | — | — | EP | claimed |