Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.51 |
| ▸ | OXTR | P30559 | 2/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423791 | 0.92 | MAPT (0.51) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL5436199 | 0.90 | OXTR (0.55) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL5433052 | 0.89 | OXTR (0.57) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL6582507 | 0.89 | MAPT (0.51) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL6585721 | 0.89 | OXTR (0.47) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL6583696 | 0.85 | OXTR (0.45) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL6584840 | 0.84 | OXTR (0.48) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL5425200 | 0.82 | OXTR (0.54) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A | |
| SCHEMBL5820186 | 0.81 | OXTR (0.66) | MAPTSMN1; SMN2OXTRAVPR1ATP53 | |
| SCHEMBL5423810 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2SCN9AOXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272468-B1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | SANOFI AVENTIS (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1272468-A1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001074775-A1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | SANOFI-SYNTHELABO (FR) | 2001-10-11 | — | — | WO | disclosed |