Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.48 |
| ▸ | CPT2 | P23786 | 3/20 | 0.47 |
| ▸ | CPT1A | P50416 | 3/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436199 | 0.95 | OXTR (0.55) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL5438791 | 0.92 | OXTR (0.48) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL5435083 | 0.89 | OXTR (0.59) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL6582219 | 0.89 | PTGDR2 (0.49) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL5425200 | 0.87 | OXTR (0.54) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL6585721 | 0.86 | OXTR (0.47) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL6581724 | 0.84 | MAPT (0.51) | OXTRAVPR1ASCN9ATP53MAPT | |
| SCHEMBL5429922 | 0.84 | OXTR (0.66) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL5820186 | 0.84 | OXTR (0.66) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL3876738 | 0.84 | OXTR (0.66) | OXTRAVPR1ACPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272468-B1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | SANOFI AVENTIS (FR) | 2004-11-17 | — | — | EP | disclosed |