Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | BRS3 | P32247 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506559 | 0.89 | BRS3 (0.40) | MEN1KMT2ABRS3MAPTALDH1A1 | |
| SCHEMBL6580124 | 0.88 | MEN1 (0.41) | MEN1KMT2ABRS3MAPTALDH1A1 | |
| SCHEMBL6588042 | 0.87 | BRS3 (0.40) | MEN1KMT2ABRS3ALDH1A1HPGD | |
| SCHEMBL6582508 | 0.86 | EDNRA (0.43) | MEN1KMT2AALDH1A1HTTEDNRB | |
| SCHEMBL8329557 | 0.85 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6577534 | 0.85 | EDNRA (0.36) | MEN1KMT2ABRS3ALDH1A1HTT | |
| SCHEMBL6580054 | 0.80 | BRS3 (0.39) | BRS3ALDH1A1HPGDKDM4EEDNRB | |
| SCHEMBL8784081 | 0.80 | MAPK1 (0.41) | MEN1KMT2ABRS3MAPTALDH1A1 | |
| SCHEMBL6579996 | 0.78 | HSP90AA1 (0.38) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6580208 | 0.77 | EDNRB (0.45) | BRS3EDNRBTP53EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804435-B1 | NOVEL IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2004-03-10 | — | — | EP | disclosed |
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |