Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582508 | 0.93 | EDNRA (0.43) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8433247 | 0.89 | BRS3 (0.39) | MEN1KMT2AMAPTEDNRAALDH1A1 | |
| SCHEMBL8330624 | 0.89 | EDNRB (0.40) | KMT2AMAPTTP53POLBEDNRB | |
| SCHEMBL8329904 | 0.88 | PPARG (0.38) | MAPTTP53POLBEDNRBEDNRA | |
| SCHEMBL8524654 | 0.87 | SMN1; SMN2 (0.39) | MEN1KMT2AMAPTTP53EDNRA | |
| SCHEMBL8431530 | 0.86 | EDNRA (0.37) | KMT2ATP53EDNRBEDNRAALDH1A1 | |
| SCHEMBL6581992 | 0.85 | MEN1 (0.42) | MEN1KMT2AMAPTTP53POLB | |
| SCHEMBL8431636 | 0.83 | ALDH1A1 (0.40) | MEN1KMT2AMAPTTP53EDNRB | |
| SCHEMBL7495951 | 0.83 | EDNRA (0.46) | EDNRBEDNRAALDH1A1KDM4EHPGD | |
| SCHEMBL6580208 | 0.83 | EDNRB (0.45) | TP53EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |