Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102465 | 0.86 | CA12 (0.50) | MEN1KMT2AL3MBTL1THRATHRB | |
| SCHEMBL12493300 | 0.84 | TAS1R3 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4328843 | 0.83 | CA12 (0.55) | MEN1KMT2AL3MBTL1CA12CA1 | |
| SCHEMBL1613775 | 0.82 | MEN1 (0.76) | MEN1KMT2AGAAKDM4ETP53 | |
| SCHEMBL29351129 | 0.82 | MEN1 (0.76) | MEN1KMT2AGAAKDM4ETP53 | |
| SCHEMBL642682 | 0.82 | HSD17B2 (0.56) | MEN1KMT2AHSD17B2GAAPDE4A | |
| SCHEMBL4344594 | 0.82 | HSD17B2 (0.56) | MEN1KMT2ATHRATHRBHSD17B2 | |
| SCHEMBL10118736 | 0.81 | CA12 (0.59) | MEN1KMT2AL3MBTL1CA12CA1 | |
| SCHEMBL642011 | 0.80 | HSD17B2 (0.47) | L3MBTL1THRATHRBHSD17B2TP53 | |
| SCHEMBL9174312 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AL3MBTL1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784052-B1 | Quinoline derivatives as antagonists of leukotriene d4, compositions containing the same and processes for their preparation | AVENTIS HOLDINGS INC (US) | 2004-09-01 | — | — | EP | disclosed |