Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 14/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.80 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582012 | 0.89 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6577718 | 0.88 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6582852 | 0.88 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6581749 | 0.87 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6580540 | 0.87 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6577740 | 0.86 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6577688 | 0.83 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6577905 | 0.78 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6579915 | 0.76 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6577785 | 0.76 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | claimed |
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | disclosed |