Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 19/20 | 1.00 |
| ▸ | HTR1A | P08908 | 15/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.98 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577718 | 1.00 | ADRA1B (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6582012 | 0.99 | ADRA1B (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6577740 | 0.97 | ADRA1B (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6582295 | 0.88 | HTR1A (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6580540 | 0.88 | HTR1A (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6577905 | 0.88 | HTR1A (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6581749 | 0.88 | ADRA1B (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6577806 | 0.87 | ADRA1B (0.98) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6579915 | 0.85 | ADRA1B (1.00) | ADRA1BHTR1AADRA1AADRA1D | |
| SCHEMBL6577785 | 0.85 | ADRA1B (1.00) | ADRA1BHTR1AADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | claimed |
| EP-1200406-A1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 2002-05-02 | — | — | EP | claimed |
| WO-2001005765-A1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2001-01-25 | — | — | WO | claimed |
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | disclosed |