Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | CRHBP | P24387 | 3/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711268 | 0.84 | MAPT (0.65) | SMN1; SMN2KMT2AMEN1MAPTCRHBP | |
| SCHEMBL8004123 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AMEN1MAPTGAA | |
| SCHEMBL6581538 | 0.81 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AMEN1MAPTGAA | |
| SCHEMBL6576745 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1MAPTHTT | |
| SCHEMBL11170835 | 0.80 | NPSR1 (0.60) | SMN1; SMN2KMT2AHTTL3MBTL1CYP1A2 | |
| SCHEMBL7997377 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AMEN1MAPTGAA | |
| SCHEMBL6586156 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AMEN1MAPTCRHBP | |
| SCHEMBL1967194 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2KMT2AMEN1MAPTCRHBP | |
| SCHEMBL6577276 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2AMEN1MAPTCRHBP | |
| SCHEMBL1974278 | 0.78 | L3MBTL1 (0.50) | SMN1; SMN2KMT2AMEN1MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |